The graft:
- Based on a unique 3D stable matrix technology
- Consists of two components: an absorbable gel-textile-matrix and autologous in vitro seeded chondrocytes
- Is mechanically stable and flexible
- Has a size of 20 x 30 x 1,1 mm
- Contains 28.8 millions autologous in vitro expanded chondrocytes
- Is available for the patient approx. 4-5 weeks from patient’s biopsy delivery
- Is manufactured and distributed according to the current requirements of the German Drugs Law and the European GMP standards (Good Manufacturing Practice)
The application:
- For the first time with BioSeed®-C a chondrocytes graft can be fixed to the subchondral bone in a secure way
- This makes it possible to treat defects without intact cartilage rims
- The graft can be cut to fit the size of the cartilage defect
- BioSeed®-C has no orientation: cells are evenly distributed for an easier handling
- The transplantation can be done by arthroscopy or by arthrothomy
The results:
- The absorbable matrix dissoves in 4-6 months after transplantation
- In the meanwhile hyaline cartilage grows and evenly fills the cartilage damage
- In numerous studies a significant improvement of clinical parameters could be reported also in the long term
